An Occasional Nip Does Some Good

By: Paul Hetzler

Volume 16, Issue 2, February 2021

A friend who once worked nights in a resort bar was asked by a patron where to find “weed.” As it happened, my pal’s day job was farming, and his truck had plenty of hay chaff, so as a prank he bagged some and gave it to the grateful chap. The next night the guy wanted more, claiming it was great, much to my friend’s surprise. “Who knows what else might be growing in the alfalfa,” he quipped to me with a shrug.

My first thought was that it could have been catnip (Nepeta cataria), a member of the mint family, which has marked opioid-like effects on cats, and mild sedative effects on humans. It can be found in many herbal tea blends designed to help with stress or insomnia. Native to Europe, Africa, and Asia, catnip long ago became naturalized in the Americas, and now grows pretty much everywhere except for the Arctic and high elevations. In fact, if you live in the country, you likely have some growing on your land.

Most of us have seen cats high on catnip, or at least seen videos of the antics cats pull after sniffing nepetalactone, the volatile compound in catnip that makes felines feel fine. Of course cat brains don’t respond to drugs like ours do. Most popular drugs act fairly directly on our brains to enhance “feel good” chemicals such as dopamine and endorphins. Nepetalactone, however acts on a cat’s brain through a series of Rube Goldberg-like pathways that stretch from the olfactory bulb to the amygdala and then to the hippocampus, which triggers an endocrine reaction in the pituitary gland to produce a sexual pheromone. In short, catnip feels as good as sex. To cats, anyway.

Cats after consuming catnip are a sight to behold - but have you ever wondered about the science behind their strange behaviour? Watch and learn. Subscribe:​ Watch more: Planet Earth​ Blue Planet​ Planet Earth II​ Planet Dinosaur​ ( Posted May 28, 2020) (Permission requested Feb. 8, 2021)

Roughly 75% of adult cats – domestic and wild – are affected by catnip. They typically roll around, salivate, and vocalize for about ten minutes in response to a good catnip toot. From a survival perspective, it seems like a bad idea that most cats willingly get wasted, even for a short time, because it makes them potentially vulnerable for a while, not to mention putting a damper on hunting.

The answer has been in front of us for some time, although it was just recently that all the pieces came together in a controlled study. In August 2001, the results of a catnip study were presented at the annual meeting of the American Chemical Society, the world’s largest scientific society. In truth, it was a nepetalactone study, minus the cats, but cool anyway. Iowa State University researchers found that nepetalactone is ten times better than DEET at repelling mosquitoes! Not only is that impressive, it leaves me wondering why haven’t switched from DEET to catnip.

It could be because catnip has relatively low levels of nepetalactone compared to the concentrations used in the study. People were quick to connect the dots and hypothesize that maybe cats roll in catnip to repel insects. Given that we’ve known for twenty years that the plant might help keep the 'skeeters away from Fluffy, it does seem odd that it took so long to find out for sure.

Webpage, "Science Advances." Science Advances is a peer-reviewed multidisciplinary open-access scientific journal established in early 2015 and published by the American Association for the Advancement of Science.

We already know that to a cat, nepetalactone feels as good as a roll in the hay. Now, a five-year study out of Japan, released in January 2021, proves that a roll in catnip keeps at least half the mosquitoes away as compared to non-catnipped cats. Masao Miyazaki, a biologist with Iwate University, studied domestic cats as well as four species of big cats in zoos, to learn about their degree of attraction to catnip, and to measure their blood levels of “feel-good” chemicals before and after sniffing the plant. The research team placed sedated cats, some allowed a romp in the catnip beforehand and some not, into chambers full of mosquitoes, and counted the numbers of bites each group received. They proved that cats which roll in catnip not only feel happier, they get far fewer bites than sober cats. Miyazaki’s team also patented a new nepetalactone-based insect repellant, which may have been the point to begin with.

If you have a cat, consider planting catnip in the garden next year – seeds are commercially available, and inexpensive. It can provide tea (and amusement) for you, and mosquito-free, happy feelings for your cat.

By Paul Hetzler

Paul Hetzler is an arborist and former Cornell Cooperative Extension Educator. He did try catnip, but claims he didn’t inhale.

Editor's note:

If you like Paul Hetzler's writing then you must get his book, Shady Characters: Plant Vampires, Caterpillar Soup, Leprechaun Trees and Other Hilarities of the Natural World."  It is available on, (Canadian), and the convenient (Kindle).  Once you get it, let me know how many times you smiled and/or laughed out loud... As well, see Paul's other TI Life submissions here:

See the TI Life Book Review for Shady Characters, "Books for your Library," December 2019 

Posted in: Volume 16, Issue 2, February 2021, Nature

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Paul Hetzler

Paul Hetzler is a Horticulture and Natural Resources Educator at Cornell Cooperative Extension, in Canton, NY. He is the author of "Shady Characters," and the website “Where the Wild Words Are."

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